Anterior Skull Base Glomangioma-Induced Osteomalacia

نویسندگان

  • Malia S. Gresham
  • Steven Shen
  • Yi J. Zhang
  • Kelly Gallagher
چکیده

Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (first reported in English) of paranasal sinus glomangioma-induced osteomalacia in a 42-year-old man. He presented with weakness and multiple spontaneous fractures, and was found to have an ethmoid sinus glomangioma with intracranial extension. The tumor was removed via endoscopic endonasal approach to the anterior skull base, which resulted in complete resolution of symptoms and no further evidence of disease 1 year postoperatively.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report

UNLABELLED INTRODUCTION Tumor-induced osteomalacia is a paraneoplastic syndrome of hypophosphatemia. Osteomalacia causes multiple bone fractures and severe pain. CASE PRESENTATION We report the case of a 57-year-old Japanese man with tumor-induced osteomalacia associated with a middle cranial fossa bone tumor. The tumor was successfully resected by using a middle fossa epidural approach. H...

متن کامل

Fungal infection of the sinus and anterior skull base

  Abstract   Background: Invasive fungal infection is an opportunistic infection caused commonly   by mucoraccae and aspergillus. It mostly occurs in patients with underlying disease.   Since it has a high mortality and morbidity rate, considering a treatment strategy seems   necessary.   Objective: Since there has not been a clear protocol for treating these patients, we decided   to establish...

متن کامل

Phosphaturic mesenchymal tumour of the sinonasal area: case report and review of the literature

BACKGROUND Oncogenous osteomalacia (OOM), which is also known as tumour-induced osteomalacia, is a rare condition associated with a neoplasm and a related systemic bone demineralization caused by renal phosphate wasting. OOM usually occurs in association with a variety of different mesenchymal tumours, and they were categorized into four distinct morphological patterns which they termed "phosph...

متن کامل

Endoscopic management of cerebrospinal fluid rhinorrhea from anterior skull base defects

  Abstract   Background: Over the past 20 years, the minimally invasive endoscopic approach   has gained widespread acceptance. The study was performed to evaluate the   diagnostic method and the success rate of endoscopically diagnosed and treated CSF   rhinorrhea, and also investigations such as leakage site and etiologic factor.   Methods: This retrospective CSF leakage management review of ...

متن کامل

Integrated Anterior, Central, and Posterior Skull Base Unit – A New Perspective

The skull base is one of the most complex anatomical regions and forms the floor of the cranial cavity. Skull base surgery involves open, microscopic, and endoscopic approaches to the anterior, middle, or posterior cranial fossa. A multispecialty team approach is essential in treating patients with skull base lesions. Traditionally, rhinologists are involved in providing access to anterior skul...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 78  شماره 

صفحات  -

تاریخ انتشار 2017